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Online Content

In these strange times, when COVID-19 is determing where and how we work, NAVBO is here to support the vascular biology community by offering online content for your use in teaching or just filling the gap caused by missed meetings. 

NEW - 

Summer Camp

Get all the basics on Vascular Development, Signaling, Inflammation and Bioengineering and Matrix Biology.

Camp starts June 22 and ends July 1 - this is an online event and registration is free!

We are also accepting abstracts.

Go to https://www.navbo.org/events/summer-camp

 

The COVID-19-pericyte hypothesis
Christer Betsholtz, Uppsala University

Dr. Betsholtz will discuss his recent publication: https://biorxiv.org/cgi/content/short/2020.05.11.088500v1

For information about this webinar, go to http://www.navbo.org/covid19-webinar 

Join us June 10 at 1:00pm ET
https://attendee.gotowebinar.com/register/1152330374280789259 

And still available:

Recording - Current Understanding of COVID-19 Pathology

Recording is available at https://attendee.gotowebinar.com/register/4966709933337011216
Presentations:
Clinical Trials for COVID-19 by Vinicio de Jesus Perez, Stanford University
What are we Learning from COVID-19 Autopsies by William A. Muller, Northwestern University
COVID-19 and NIH-funded research by Zorina Galis, NHLBI/NIH

Dr. Galis' slides with helpful links from NIH are available here.


Webinars  

In addition to our upcoming webinars with Martin Schwartz (May 14) and Mary Wallingford (June 11), don't forget we have recordings of all past webinars from Ondine Cleaver in March 2018 through Courtney Griffin on Apri 2.  See www.navbo.org/events/webinars for all of the recordings.

Note to members:  if you would like to use any of the recorded webinars for teaching purposes or to share with your trainees, please contact Bernadette (This email address is being protected from spambots. You need JavaScript enabled to view it.) for access.


Webinar Live Discussions    

We are repurposing some of our recorded webinars and will bring the presenters together for live discussions.  Participants will watch designated recorded webinars prior to the live discussion and then log into a webinar for a 30-minute discussion with the presenters.  The groups will include the following topics: Vascular Development, Lymphatics, Vascular Malformations, Mural cells/Pericytes and Metabolism.

Download our guidelines for participation.

NEW -

Tissue Stiffness Live Discussion - June 1 at 1:00pmET

Webinars included are:

microRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis
Presenter: Stefania Nicoli, Yale University Cardiovascular Research Center
https://attendee.gotowebinar.com/register/107540330265488385

Matrix remodeling and integrin signaling in endothelial function and dysfunction
Presenter: Martin Schwartz, Yale University Cardiovascular Research Center
https://register.gotowebinar.com/register/3477120166408244994

Elastic Fibers and the Mechanics of Maturing Arteries
Presenter: Jessica Wagenseil, Washington University in St. Louis
https://attendee.gotowebinar.com/recording/1037384113123170817

Please review their recorded webinars prior to the live discussion on June 1 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/1110990936216173324

The session will be moderated by Anjelica Gonzalez, Yale School of Medicine

Development in Cardiovascular Disease - June 15 at 1:00pmET

Webinars included are:

Coronary Development and Regeneration
Presenter: Kristy Red-Horse, Stanford University
https://attendee.gotowebinar.com/register/1089242591412151298

Lacteal Junction Zippering Protects Against Diet-Induced Obesity
Presenter: Anne Eichmann, Yale University
https://attendee.gotowebinar.com/register/5601891191238680067

Please review their recorded webinars prior to the live discussion on June 15 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/4538290725775224587

The session will be moderated by Nicholas Chavkin, University of Virginia

 

Past Sessions:

Mural Cells and Pericytes - April 13 at 1:00pmET

Webinars included are: 

Pericyte Alk5/Timp3 Axis Contributes To Endothelial Morphogenesis In The Developing Brain
Presenter: Daniel Grief, Yale School of Medicine
https://attendee.gotowebinar.com/recording/926504972131100162

Mural Cell SDF1 Signaling Is Associated with The Pathogenesis of Pulmonary Arterial Hypertension
Presenter: Ke Yuan, Boston Children's Hospital
https://attendee.gotowebinar.com/recording/8752166838060677635

Please review their recorded webinars prior to the live discussion on April 13 at 1:00pm

In addition, and to make this discussion even more relevant, we will also discuss the following article, "The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2," which is online at https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvaa078/5813131

Register for the live discussion: https://attendee.gotowebinar.com/register/6007870478628922893

Metabolism - April 15 at 1:30pmET

Webinars included are: 

Lipid Metabolism by the Endothelium
Presenter: William C. Sessa, Yale School of Medicine
https://attendee.gotowebinar.com/recording/5157265185721985542

Non-Coding RNA Regulation of Lipid Metabolism and Atherosclerosis
Presenter: Carlos Fernández-Hernando, Yale School of Medicine
https://attendee.gotowebinar.com/recording/6308252652781821195

Endothelial Regulation of Metabolic Homeostasis
Presenter: Hyung Chun,Yale School of Medicine
https://attendee.gotowebinar.com/recording/6661343221250423819

Please review their recorded webinars prior to the live discussion on April 15 at 1:30pm

Register for the live discussion: https://attendee.gotowebinar.com/register/8605368842832519694

Lymphatics - April 20 at 1:00pmET

Webinars included are: 

Lymphatic Vessels and Vanishing Bones: Animal Models of Lymphatic Anomalies with Bone Involvement
Presenter: Michael Dellinger, UT Southwestern Medical Center
https://attendee.gotowebinar.com/register/3430655889238497537

Wnt/ß-catenin signaling, mechanotransduction and lymphatic vascular development
Presenter: Sathish Srinivasan, Oklahoma Medical Research Foundation
https://attendee.gotowebinar.com/register/1072305712421262851

New Insights into Lymphatics and Lymphatic-related Cells from the Zebrafish
Presenter: Brant Weinstein, NICHD/NIH
https://attendee.gotowebinar.com/register/7766478852791391747

Please review their recorded webinars prior to the live discussion on April 20 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/6426520526070000397

Vascular Development - April 27 at 1:00pmET

Webinars included are: 

How Blood Vessels Control Their Own Destiny
Presenter: Victoria Bautch, McAllister Heart Institute, UNC Chapel Hill
https://attendee.gotowebinar.com/recording/3434643827823707905

What Chromatin Remodelers Can Teach Us About Vascular Development and Integrity
Presenter: Courtney Griffin, Oklahoma Medical Research Foundation
https://attendee.gotowebinar.com/register/261493956150688514

GTPase regulation of actomyosin during blood vessel tubulogenesis
Presenter: Ondine Cleaver, Department of Molecular Biology, UT Southwestern Medical Center
https://attendee.gotowebinar.com/recording/58696717993432839

Please review their recorded webinars prior to the live discussion on April 27 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/6959889218702380300

Vascular Malformations - May 4 at 1:00pmET

Webinars included are: 

The Gut-Brain Axis in Cerebral Cavernous Malformation
Presenter: Mark Kahn, University of Pennsylvania School of Medicine
https://attendee.gotowebinar.com/recording/5995851715459119874

Capillary malformations: From somatic GNAQ mutation to disrupted endothelial function
Presenter: Joyce Bischoff, Boston Children's Hospital, Harvard Medical School
https://attendee.gotowebinar.com/recording/3967197780746857473

Angiopoietin-2 inhibition rescues arteriovenous malformation in a Smad4 HHT mouse model
Presenter: Stryder Meadows, Tulane University
https://attendee.gotowebinar.com/recording/1545978617300324355

Please review their recorded webinars prior to the live discussion on May 4 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/1024154805455271435

Biomechanics and Tissue Engineering - May 11 at 1:00pmET

Webinars included are:

Engraftment of Bioengineered Vascular Networks
Presenter: Juan Melero-Martin, Boston Children's Hospital
https://attendee.gotowebinar.com/register/5426799458240629506

Cardiovascular Mechanics and Extracellular Vesicles
Presenter: Joshua D. Hutcheson, Florida International University
https://attendee.gotowebinar.com/register/3198752399220757005

Elastic Fibers and the Mechanics of Maturing Arteries
Presenter: Jessica Wagenseil, Washington University
https://attendee.gotowebinar.com/recording/1037384113123170817

Please review their recorded webinars prior to the live discussion on May 11 at 1:00pm

Register for the live discussion: https://attendee.gotowebinar.com/register/6400522574140613644

YouTube Channel

Visit the NAVBO YouTube Channel - https://www.youtube.com/channel/UCwS-fTuzq51pBUmCe6G7S-g/playlists

We have "playlists" covering the following areas:
Pericytes
Cardiac Development
Lymphatic System
Vasculogenesis/Angiogenesis
VEGF/VEGFR2
Stroke
Aneurysm/Atherosclerosis
Tumor Angiogenesis
Anatomy and Physiology

These are videos vetted by our Education Committee that are already on YouTube.  Feel free to subscribe!


Online Journal Clubs  

Our next Journal Club is May 21. See our forum for details.

Our journal clubs have also been recorded.  Members can access those recordings here: https://www.navbo.org/forum/journal-club

Past papers covered were:

Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues

This journal club will take place on May 21 from 1-2pmET

This NAVBO Journal Club will feature the paper: "Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues," which can be accessed at this URL https://www.sciencedirect.com/science/article/pii/S2211124720303181
There will be a 30-minute presentation by: Brahma Mulugu, PhD followed by 30 minutes of Q&A from the audience.
Feel free to post comments, questions, etc. in the NAVBO forum at https://www.navbo.org/forum/05-20journal-club before the presentation so that they can be addressed during the presentation.

Age Associated Mitochondrial Dysfunction Accelerates Atherogenesis

March 2020:
Age Associated Mitochondrial Dysfunction Accelerates Atherogenesis, Daniel J. Tyrrell, Muriel G. Blin, Jianrui Song, Sherri C. Wood, Min Zhang, Daniel A. Beard, Daniel R. Goldstein, Circulation Research,
https://doi.org/10.1161/CIRCRESAHA.119.315644
Circulation Research. 2020;126:298–314

Apelin+ Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury

January 2020:
Apelin+ Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury. Chen Q, Liu Y, Jeong HW, Stehling M, Dinh VV, Zhou B, Adams RH. Cell Stem Cell. 2019 Dec 5;25(6):768-783.e6. doi: 10.1016/j.stem.2019.10.006. Epub 2019 Nov 21 PMID: 31761723 DOI: 10.1016/j.stem.2019.10.006

Migratory and Dancing Macrophage Subsets in Atherosclerotic Lesions

November 2019:
Migratory and Dancing Macrophage Subsets in Atherosclerotic Lesions. Sara McArdle, Konrad Buscher, Yanal Ghosheh, Akula Bala Pramod, Jacqueline Miller, Holger Winkels, Dennis Wolf, and Klaus Ley. Originally published: 9 Oct 2019, Ahead of Print, Circulation Research. https://doi.org/10.1161/CIRCRESAHA.119.315175 PMID: 31594470

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium

September 2019:
Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium. Ricard N, Scott RP, Booth CJ, Velazquez H, Cilfone NA, Baylon JL, Gulcher JR, Quaggin SE, Chittenden TW, Simons M. J Exp Med. 2019 Aug 5;216 (8 ):1874-1890. doi: 10.1084/jem.20182151. Epub 2019 Jun 13. PMID: 31196980

Members:  if you would like to use any of the recorded Journal clubs for teaching purposes or to share with your trainees, please contact Bernadette for access. 


Online Mini-Symposia  

We are no longer accepting submissions for mini-symposia.  If you would like to present your work, please submit an abstract to Vascular Biology 2020, which will be a virtual event.

Go to https://www.navbo.org/events/vb2020/vb2020abstracts

 

NEW -

New Strategies for Vascular Intervention

New Strategies for Vascular Intervention 

May 28 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/2388714707154302734
The session will feature the following presentations:
Lysolipid Signaling in Atherosclerosis (Susan Smyth, University Kentucky)
Suppression of endothelial AGO1 promotes adipose tissue browning and improves metabolic dysfunction (Xiaofang Tang, City of Hope)
Sonoporation increases doxorubicin uptake in neuroblastoma xenografts by enhancing vascular permeability (Sonia Hernandez, University of Chicago
Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization (Partha Roy, University of Pittsburgh)
The session will be moderated by Lisandra Vila Ellis, MD Anderson

 

Past Sessions: 

Vascular Specification and Development

Vascular Specification and Development

April 21 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/3821322281504631809
The session will feature the following presentations:
Renal stromal netrin-1 signaling drives kidney arterial development (Xiaowu Gu, UT Southwestern)
Inhibition of Notch signaling in pericytes leads to AVM-like lesions (Taliha Nadeem, University of Illinois, Chicago)
Dach1 Promotes Coronary Artery Endothelial Cell Specification (Brian Raftrey, Stanford University)
Pro-angiogenic properties of Purified Exosome Product (PEP) (Ao Shi, Mayo Clinic)
The session will be moderated by Kayla Bayless, Texas A&M University

Endothelial challenge and mural cell interactions

Endothelial challenge and mural cell interactions

April 23 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/5329832444356202251
The session will feature the following presentations:

Constitutive Active Mutant TIE2 Induces Enlarged Vascular Lumen Formation with Loss of Apico-basal Polarity and Pericyte Recruitment (Elisa Boscolo, Cincinnati Children's Hospital)
Emerging mechanisms of intercellular junction remodeling (Arie Horowitz)
Quantitatively defining spatial patterns of myoendothelial junctions in the arterial wall (Claire Ruddiman, University of Virginia)

The session will be moderated by Xiaowu Gu, UT Southwestern Medical Center

Endothelial cells in vasculogenesis and organogenesis

Endothelial cells in vasculogenesis and organogenesis

April 28 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/4163437524323887371
The session will feature the following presentations:
Intercalation of vascular progenitors into functional blood vessels represents a novel mechanism of vascular growth (Sanjeeva Metikala, Cincinnati Children's Hospital Medical Center)
The formation of lymphatics during mammalian kidney organogenesis (Daniyal Jafree, University College London)
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung (Lisandra Vila Ellis, MD Anderson Cancer Center)
The session will be moderated by Theresa Dinh, Stanford University

Vascular stress and mechanobiology

Vascular stress and mechanobiology

April 30 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/4113356968701975563
The session will feature the following presentations:
Non-proteolytic ubiquitination in oxLDL/disturbed flow-induced endothelial activation (Dongdong Wang, Louisiana State University, Health Sciences Center-Shreveport)
Staphylococcus aureus toxin alpha hemolysin increases endothelial cell proliferation and disrupts pericyte coverage of arteries in a murine retinal model (Sonia Hernandez, University of Chicago)
Flow-sensitive PLPP3 regulates YAP/TAZ mechano-responses in vascular endothelium (Jiayu Zhu, University of Chicago)
The session will be moderated by Bill Hughes, Medical College of Wisconsin

Cardiovascular health and disease

Cardiovascular health and disease

May 12 at 1:00pmET

Register today: https://attendee.gotowebinar.com/register/6819372732402903051
The session will feature the following presentations:
Single-cell Transcriptomes Identify Abnormal Endothelial Subpopulations in Pulmonary Arterial Hypertension (Zhiyu Dai, University of Arizona)
Mechanisms governing Microvascular adaptation: Governing mechanism of human microvascular endothelial function in coronary Artery Disease  (Andreas Beyer, Medical College of Wisconsin)
Premature induction of Lysyl Oxidase drives early arterial stiffening in Hutchinson-Gilford Progeria Syndrome (HGPS) (Ryan von Kleeck, University of Pennsylvania)
The session will be moderated by Bill Hughes, Medical College of Wisconsin and Redouane Aherrahrou, University of Virginia

 

Check back for presentation and registration information.

These sessions are not recorded, but are open to the entire vascular biology community.   

We are seeking contributors for additional content.  If you would like to present your work in an upcoming mini-symposium, please complete our online submission form.

 

Please participate! 

If you have other ideas to further engage the vascular biology community, please contact Bernadette (This email address is being protected from spambots. You need JavaScript enabled to view it.) or Ondine Cleaver, President of NAVBO (This email address is being protected from spambots. You need JavaScript enabled to view it.).

 

Stay healthy, be safe and be careful!