Vasculata 2017
July 24-27, 2017
Chicago, IL
Program
MONDAY, JULY 24
Session I: Tunica Media, Tunica Adventitia, Tunica Intima, and Lineage Markers
Chairs: Asrar B. Malik and Jan Kitajewski, University of Illinois, Chicago
7:50am - 10:00am
Welcome
Kishore Wary, University of Illinois, Chicago
Development of Vascular Endothelial Cells
Kishore Wary, University of Illinois, Chicago
The Development of Endothelial and Blood Lineages in the Zebrafish
Owen Tamplin, University of Illinois, Chicago
Zebrafish Vascular System
Ramani Ramchandran, Medical College of Wisconsin
Genetic Tools to Study Endothelial Cell Development
***Ralf Adams, Max Planck Institute, Münster
Coffee break - 10:00 -10:20am
Session II: Endothelium: Endothelial Barrier Function, Permeability, and Vasoactivity
Chairs: Asrar B. Malik and Dolly Mehta, University of Illinois, Chicago
10:20am - 12:20pm
Lineage Tracing Studies in Microvessel Repair
Asrar B. Malik, University of Illinois, Chicago
Focal adhesion kinase Regulation of Endothelial Barrier Function
Dolly Mehta, University of Illinois, Chicago
Transcytosis: Caveolae-mediated Transendothelial Transport
Richard D. Minshall, University of Illinois, Chicago
Local Ca2+ signaling networks in vascular endothelium
Swapnil K. Sonkusare, University of Virginia
Pizza Lunch - 12:20-1:20pm
Session III: Structure/function of Smooth Muscle cells and Pericytes
Chairs: Jan Kitajewski and Henar Cuervo Grajal, University of Illinois, Chicago
1:20pm - 3:20pm
Role of Pericytes and Mural Cells in the Vasculature
Henar Cuervo Grajal, University of Illinois, Chicago
Tie2 Signaling in Vascular Development and Disease
Susan Quaggin, Northwestern University
Serum Response Factor: The Master Coordinator of Vascular Smooth Muscle Phenotype
B. Paul Herring, Indiana University School of Medicine
TGF-beta Signaling in Smooth Muscle Differentiation and Vascular Remodeling
Shiyou Chen, University of Georgia
Poster Viewing
3:30-6:00pm
Dinner on your own
TUESDAY, JULY 25
Session IV: Arterial Branching, Capillaries, Collaterals, Venules and Veins, and Regeneration
Chairs: Jan Kitajewski and Asrar B. Malik, University of Illinois, Chicago
8:00am - 10:00am
Endothelial Cell Fate Determination and Specialization
Jan Kitajewski, University of Illinois, Chicago
Angiogenesis as a Systemic Process, Paracrine Function of Myeloid Cells
Tatiana Byzova, Cleveland Clinic, Taussig Cancer Center
Endothelial Regeneration
You-Yang Zhao, University of Illinois, Chicago
Exercise and Endothelium Dependent Vasodilation in the Human Circulation
Shane Philips, University of Illinois, Chicago
Coffee break - 10:00 -10:30am
Session V: Developmental Mechanisms and CRISPR/Cas9 in Vascular Biology
Chairs: Asrar B Malik, University of Illinois, Chicago and Courtney Griffin, Oklahoma Medical Research Foundation
10:30am - 12:00pm
CRISPR Genome Editing in the Mouse
Joseph Miano, University of Rochester
Pulmonary Circulation in the Perinatal Period
J. Usha Raj, University of Illinois, Chicago
Epigenetics & Transcription Factors in Vascular Development & Disorders
Courtney Griffin, Oklahoma Medical Research Foundation
Networking Lunch: Converse with faculty and peers (lunch will be provided)
12:15-1:30pm
Workshop Session I
1:30pm - 2:30pm
Career Development: Transitions from grad to post-doc, post-doc and beyond
Panel Discussion
1:45pm - 2:45pm
Workshop: Transendothelial Electrical Resistance Analysis (TER)
Session VI: Developmental Disorders
Chairs: Jan Kitajewski, University of Illinois, Chicago and Guillermo C. Oliver, Northwestern University
3:00pm - 4:30pm
Biology of FoxC2 in Vascular Lymphatic Development
Tsutomu Kume, Northwestern University
Epsins and Angiogenesis
Hong Chen, Boston Children's Hospital,Harvard Medical School
Characterization of the Early Steps Controlling Lymphatic Vasculature Formation
Guillermo C. Oliver, Northwestern University
Dinner on your own
WEDNESDAY, JULY 26
Session VII: Inflammatory Interactions of Endothelium with Leukocytes and Immune system
Chairs: Asrar B Malik and Richard Minshall, University of Illinois, Chicago
8:00am - 10:30am
Platelet-neutrophil Interactions Under Thromboinflammatory Conditions
Jaehyung Cho, University of Illinois, Chicago
Preface to Initiation of Leukocyte Recruitment in Inflammation
Ronen Sumagin, Northwestern University
Leukocyte Transendothelial Migration and Movement Across the Basement Membrane
William Muller, Northwestern University
Mechanobiology of Cell Trafficking in Confined Space
***Jae-Won Shin, University of Illinois, Chicago
The Matrisome Project: Novel Tools and Methods to Study the Extracellular Matrix
Alexandra Naba, University of Illinois, Chicago
Workshop Session II
10:30am - 11:30am
Career Development
Lab Management Panel Discussion
Workshops
10:30am - 12:00pm
Multiphoton 3D Imaging of the Blood Vessels (IMARIS)
Peter Toth, University of Illinois, Chicago
11:15am - 1:45pm
Ways to Assess Vascular Inflammation and Thrombosis - Intravital Microscopic Imaging
Jaehyung Cho, University of Illinois, Chicago
Group 1: 11:15-12:15; Group 2: 12:45-1:45
Lunch on your own - 12:00-1:45pm (depending on workshops you are attending)
Session VIII: Cardiovascular Disease: Inflammation, Atherosclerosis, Hypertension, and Angiogenesis
Chairs: William Muller, Northwestern University and Irena Levitan, University of Illinois, Chicago
2:00pm - 4:30pm
Unmasking the Role of the “Anti-angiogenic” VEGF165b in Ischemic Muscle
Brian Annex, University of Virginia
VEGF Signaling at the Cornea: Angiogenic vs. Neurogenic Functions
Mark I. Rosenblatt, University of Illinois, Chicago
Rap1 Signaling in the Development of Blood Vessels and Homeostasis
Magdalena Chrzanowska-Wodnicka, Medical College of Wisconsin
Role of Flow and Stress in Atherosclerosis
Irena Levitan, University of Illinois, Chicago
How do pico Newton forces affect vascular function?
Deborah Leckband, University of Illinois Urbana-Champagne
Group Dinner
West Campus Student Center
6:00pm - 9:00pm
Special Guest Speaker: Mary Woolley, President and CEO, Research!America
Your Role in Changing Hearts and Minds for Science
THURSDAY, JULY 27
Session IX: Translational Cardiovascular Medicine and Big Data
Chairs: James K Liao, University of Chicago & Jalees Rehman, University of Illinois, Chicago
8:00am - 1:00pm
Endothelial Heterogeneity: Physiological Relevance and Transcriptomics
Jalees Rehman, University of Illinois, Chicago
Quantitative + Computational Biology of Angiogenesis
Princess U II Imoukhuede, University of Illinois at Urbana-Champaign
Can we model arrhythmia mechanisms using hiPSC-derived atrial cardiomyocytes?
Dawood Darbar, University of Illinois
Preface to Endothelial Dysfunction and Vascular Disease
James K Liao, University of Chicago
Unraveling Cardiovascular Disparities: From the Community to the Bench and Back
Clyde Yancy, Northwestern University
“One Brave Idea in Coronary Artery Disease”
Calum MacRae, Brigham & Women's Hospital, Harvard University
***Live webcast presentations
Funding for this conference was made possible (in part) by 1 R13 HL137360-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the department of health and human services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
