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Vasculata

Novel insights in Vascular Biology – from Bench to Bedside

Stanford University
July 22-25, 2024

ORGANIZERS:

Joyce Teng, D.V.M., M.D., Ph.D.
Professor of Dermatology and Pediatrics
Edda Spiekerkoetter, M.D.
Associate Professor of Medicine
Joseph Wu, M.D., Ph.D.
Director, Stanford Cardiovascular Institute
Simon H. Stertzer, MD, Professor of Cardiovascular Medicine & Radiology

Preliminary Program

Monday, July 22: Basic Vascular Biology and Recent Innovations
8:30amOpening remarks
8:45 – 9:30amSpecial Lecture: Single cell dissection of vascular biology and disease
Mark Krasnow, Stanford University
9:30 -10:00amThe cellular heterogeneity of a blood vessel (endothelial cells, smooth muscle cells, pericytes, fibroblasts)
Ke Yuan, Boston Children’s Hospital
10:00-10:30amVascular development in vivo and using the knowledge to differentiate hPSCs into artery and vein ECs in vitro
Lay Teng Ang, Stanford University
10:30 -10:45amCoffee Break – Discussion
10:45 – 11:45amPoster Session 1
11:45am – 12:30pmSpatial transcriptomics
Michael Snyder, Stanford University
12:30-1:30pmLunch
1:30- 5:00pmWorkshops
 scRNA sequencing, nuclear sequencing – platforms, Interpretation, validation – important aspects to consider
Leader: Amy Tian, Stanford University
 Multiplex spatial imaging techniques
Leader: Adam Andruska
 2D versus 3D imaging [in collaboration with Leica (confocal microscopy) and Imaris (imaging software)]
Leader: TBD
5:00-5:30pmThe Pathologist’s View: Employing a variety of protein and RNA in situ techniques to characterize endothelial cells and pericytes of the liver in vascular disorders
Serena Tan, Stanford University
5:30-6:00pmCareer Development
Decoding Career Paths: What makes becoming an academic PI appealing in 2024?
Leaders: Mingxia Gu, Cincinnati Children's Hospital Medical Center and Ke Yuan, Boston Children’s Hospital
 
Tuesday, July 23: Vascular Diseases and Disease Models
8:30 – 9:15amSpecial Lecture: Coronary artery development: health – disease
Kristy Red-Horse, Stanford University
9:15 – 10:00amLineage labeling/3D imaging to understand neointima formation in pulmonary arterial hypertension
Maya Kumar, Stanford University
10:00 – 10:45amSelected presentations from participants
10:45 – 11:45amPoster Session 2
11:45 – 12:30pmCharacterizing genetic variation across single cells with sensitivity and accuracy to study clonal evolution for cancer and potentially vascular disorders.  Localization of somatic genetic mutations
TBD
12:30-1:30pmLunch
1:30-2:00pmCareer Development
Roadmap for a successful Physician Scientist Career
Mark Nicolls, Stanford University
2:00-2:30pmDrug repurposing for complex non-cerebral vascular malformations using a personalized approach
Joyce Teng, Stanford University
2:30-3:00pmAVM: Molecular programming of arterial-venous specification, combining mouse genetics and cutting-edge two-photon live imaging
Rong Wang, University of California, San Francisco
3:00-3:30pmCoffee Break
3:30-4:00pmInflammation mediated pulmonary hypertension as seen in Schistosomiasis
TBD
4:00-5:00pmCareer Development
Grant writing workshop - specific aims, how to write a powerful abstract
Crystal Botham
 
Wednesday, July 24: From biology to therapy
8:30 – 9:15amSpecial Lecture: Using iPSCs for drug prediction and in vitro model: disease on a chip
Joseph Wu, Stanford University
9:15 – 10:00amExploiting human iPSC derived endothelial cells to study BSL4 viruses — the deadliest viruses on Earth
Kyle Loh, Stanford University
10:00 – 10:45amSelected presentations from participants
10:45 – 11:45amPoster Session 3
11:45 – 12:30pmPre-clinical disease modeling using vascularized organoids
Mingxia Gu, Cincinnati Children’s Hospital
12:30-1:30pmLunch
1:30-2:00pmStudying endothelial-pericyte interactions in the lung and the heart: Implications to PAH Vinicio de Jesus Perez, Stanford University
2:00-2:30pmThe biology of inflammation in lymphatic disease and its implication for future pharmacological therapeutics
TBD
2:30-3:00pmRepurposing drugs as a fast-track from bench to bedside
TBD
3:00-3:30pmCoffee Break
3:30-4:00pmCareer Development
Mentorship and Sponsorship. You need both to succeed in your academic career
Edda Spiekerkoetter, Stanford University
4:00-4:30pmNovel imaging and interventional technologies to intervene on central lymphatic defects of vascular diseases
TBD
4:30-5:00pmPlatform technologies for sorting and monitoring cells at the single-cell resolution. High-throughput drug screening
TBD
5:00-5:30pmThe entrepreneurial mindset or Enhanced drug delivery approaches, 3D printing
TBD
 
Thursday, July 25: Turning promising research ideas into clinical applications
8:30 – 9:15amSpecial Lecture: From integrating pathways to developing novel therapies in pulmonary hypertension
Marlene Rabinovitch, Stanford University
9:15 – 9:45amDeveloping gene therapy strategies to reduce brain arteriovenous malformation severity
Hua Su, University of California, San Francisco
9:45 – 10:00amCoffee Break
10:00 – 10:30amThe investigator initiated clinical trial: How to get there. Basic science - patent - to clinical trial
Edda Spiekerkoetter, Stanford University
10:30 – 11:00amTBD
11:00-11:30amCareer Development
Women in Science: “I don’t do politics” is not an option
TBD
11:30-12:00pmPoster awards and closing remarks

Registration for Vasculata 2024 is open.

Early Bird Registration Rates
(early bird ends on May 31)

Trainee (students and postdocs) members of NAVBO:  $165USD ($215 after May 31)

Non-member trainees: $245USD ($295USD after May 31)

All undergraduate students: $75USD ($100USD after May 31)

NAVBO Regular Members:  $425USD ($475USD after May 31)

Non-members who are faculty, PIs, etc.:   $525USD ($575USD after May 31)

There will be a $25 fee for workshops and wet labs.  Panel discussions on career development are free.

Consider joining NAVBO to save on your registration plus receive other benefits as well - https://members.navbo.org/member-application

Special notice for students - if you identify with an underrepresented group in science (Black/African American, Latinx/Hispanic, Indigenous Peoples of America/Native American, including Native Hawaiian and Alaskan, and LGBTQ+) join NAVBO for free through our Advancing Young Voices through Diversity and Inclusion Program.  Complete the membership application here:  https://members.navbo.org/ap/Membership/Application/gLWqvZpX

REGISTER NOW

Abstracts are due May 15 by 5:00pmEDT

The submission site is open.

When preparing your abstract:

  • Abstract Size and Limitations: Titles of abstracts are limited to 250 characters; the abstract text is limited to 2,000 characters (this number includes spaces and punctuation).
  • Format: Do not include authors’ names and affiliations within the abstract body. The name of your company or institution will appear as it does in the entry you create for authors.  Remember to add yourself as an author.
  • Enter institution names exactly the same for all authors from a single institution.
  • Enter complete information for all co-authors including their email addresses.
  • Do not include references, credits or grant support in your abstract; however, these should be acknowledged within your poster.
  • Proofread abstracts carefully to avoid errors before submission. No proof pages will be sent to authors, but you can preview your abstract within the site for accuracy.
  • The presenter is responsible for expenses associated with the presentation of an abstract and attendance at the meeting (if you need financial assistance, apply for a scholarship).
  • Incomplete abstracts will be deleted on May 31, 2024.
  • All abstracts will be presented as Posters.

Topics for poster presentations are:

Bioengineering
Cardiovascular Disease
Cell Biology
Development
Inflammation
Lymphatics
Organ Specific
Signaling
Vascular Biology – Other

Submit your abstract

A number of scholarships will be available based on need.  Full scholarships will be valued at $1,000 and some partial scholarships may be available as well.

The deadline for applications is May 15.

Applications will be accepted online only through May 15.

Applications must include the following:

1) Responses to the four questions below.

  • Please provide a summary of your project in layman's terms. Describe in 300 words, the disease or basic scientific question that you are investigating, the hypothesis, methods used, results and conclusions.
  • Where do you, the applicant, see yourself in five years?  Describe in 100 words. your professional goals and plans.
  • What is the main reason that we should select you for this scholarship? Describe in 100 words, any circumstances which the committee should be informed of to make their decision. 
  • How will you spend the money? Describe in 100 words, how you will use the scholarship money.  Be as specific as possible.

2) A letter from the applicant's supervisor/PI that

  • verifies your status within the lab/department (Be specific--3rd year graduate student; post doc in lab for two years, etc.)
  • confirms that there are little to no funds available for your trainee to attend Vasculata

3.) Applicant's CV

ALL documents should be in pdf format.

Be sure you have all supporting documents on hand when completing this form.    You will not be able to save and return to the form.

All workshops will be held on Monday afternoon.  Each workshop is one hour in duration.  Due to the limited space, preregistration of $25 per workshop will be added to your registration fee.

scRNA sequencing, nuclear sequencing – platforms, Interpretation, validation – important aspects to consider
Leader: Amy Tian, Stanford University

Multiplex spatial imaging techniques
Leader: Adam Andruska, Stanford University

2D versus 3D imaging [in collaboration with Leica (confocal microscopy) and Imaris (imaging software)]
Leader: TBD

The scheduling of the above workshops has not been finalized.  

Vasculata 2024 is taking place at

Paul Brest Hall (Munger Section of Campus)
555 Salvatierra Walk, Stanford, CA 94305

Stanford Location and Parking Map: https://transportation.stanford.edu/parking/about-parking-permits/view-parking-and-circulation-map Munger is at J/9-10 coordinates on this map

Things to do at Stanford: https://community.stanford.edu/our-favorite-places

Stanford Marguerite (free campus shuttle service—no ID required): https://transportation.stanford.edu/marguerite/view-maps-and-schedules

Housing (Lodging)

The Munger Graduate Residence Halls are in very close proximity to the Paul Brest Hall and campus dining.  
Three meals a day are included with your stay - dinner on day of arrival (July 21) through lunch on last day (July 25).  

Purchase your four nights of lodging for $1,295USD within the registration process.  Partial stays are not available.  Consider that in addition to the food, the cost includes a private air conditioned room with private bathroom and is in walking distance of the meeting venue.  Hotels in the bay area may cost $450 per night.   

We will compile a list of local restaurants and diners, and links to tourist sites to help you make the most of your trip to Stanford!

Abstract submission deadline extended to May 15

Support Vasculata!
Contact Bernadette Englert

Funding for this conference was made possible (in part) by 1R13HL164033 from the National Heart Lung and Blood Institute (NHLBI). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.