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Since the late 1990ies research efforts in our laboratory have been focused on the understanding of the functions of the Collagen Triple Helix Repeat Containing-1 (Cthrc1), a molecule discovered in our laboratory in 1999 in the adventitia of injured arteries.

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Identification of pro and anti-inflammatory mechanisms in the vessel wall. Induction of the Th2 anti-inflammatory phenotype by resident vascular cells. Angiogenic mechanisms of anti-inflammatory interleukins.

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