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Midwest Programs

Training Programs in Vascular Biology


NIH T-32 Training Grant—Vascular Surgery Scientist Training Program – Northwestern University Feinberg School of Medicine

Mark K. Eskandari, M.D. or
William H. Pearce, M.D.
Division of Vascular Surgery
Northwestern University
Feinberg School of Medicine
676 N. St. Clair, #650
Chicago, IL 60611
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Program Scope and Mission – The NIH-funded Vascular Surgery Scientist Training Program at Northwestern University is a two-year mentored research training program designed for surgical residents (MD/DO) in general and vascular surgery and for PhD postdoctoral research fellows interested in vascular biology or vascular biomedical engineering careers. Our goal is to provide a seamless multidisciplinary environment in which the trainee may interact with a diverse group of distinguished research faculty. The T32 mechanism provides a stipend, tuition, fees for coursework, travel funds, and health insurance.

The key to this program is an individualized training plan developed by the mentor and trainee. The unique multidisciplinary environment provides trainees with opportunities to work with mentors from different disciplines. The goal of this program is to match the research interest of the trainee to mentors, coursework, seminars, meetings, and a research plan that will collectively provide the experience necessary to launch a successful career as a physician scientist. Trainees may select one of several tracks of study or a combination of tracks:
• Vascular biology with a basic science or translational emphasis,
• Clinical outcomes/health services research
• Biomedical devices in partnership with the Biomedical Engineering Department,
• An integrated program designed by the trainee and his/her mentors.
Trainees who select the clinical outcomes/health services research track will pursue the Master of Science in Health Services and Outcomes Research degree program at NU.
Candidates must hold either an MD, DO, or PhD degree. MD/DO candidates must have completed at least two years of clinical training prior to enrolling in the program. Candidates must be U.S. citizens, noncitizen nationals, or have been lawfully admitted for permanent residence at the time of appointment. Minorities and women are encouraged to apply. Applicants will submit a written application along with three letters of recommendation.

Research Training In Transfusion Medicine – BloodCenter of Wisconsin, Inc.

Gilbert C. White, II, MD

Attn: Portlynne Joseph/T32 Postdoc
Blood Research Institute
PO Box 2178
Milwaukee, WI 53201-2178
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Website: https://www.bcw.edu/bcw/Research/T32Fellowship/index.htm

Program Scope and Mission – Research opportunities available to trainees cover a broad range of basic and clinical research subjects relevant to transfusion medicine and hematology; including; Immunology, Vascular Biology/Hemostasis, Transfusion Medicine, Stem Cell Biology, and Clinical Research. The research training experience will be essentially full time. Trainees will be expected to gain a basic understanding of the disciplines in which they undertake their investigations, develop competency with a variety of research technologies, strengthen their grasp of their chosen research by taking selected courses in the graduate studies program of Medical College of Wisconsin, and develop the ability to conduct independent research. Time spent in fellowship training is regarded as one of several stages of professional development. Accordingly, additional tracks will be offered to selected trainees including; the opportunity 1) to apply for a Clinical Investigator Development Award (K08) for continued mentoring, 2) to apply for independent grant support, and 3) for those oriented toward a career in transfusion medicine, an opportunity for further training as a junior member of BloodCenter's medical staff. Ultimately, trainees are expected to pursue academic or alternate careers in transfusion medicine, hematology, or closely related fields.

Lung and Vascular Biology and Pathobiology - University of Illinois at Chicago

PI/Program Director:
Asrar B. Malik PhD

Dr. Asrar B. Malik
Director of Center for Lung and Vascular Biology
University of Illinois College of Medicine
Department of Pharmacology
835 South Wolcott Ave, E403 MSB
Chicago, IL 60612
Phone: 312 996-5672
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Program Scope and Mission – The NIH-funded UIC vascular biology training program is currently in its 25th year, providing comprehensive and cutting-edge training in vascular biology. Research topics include mechanisms of vascular regeneration, the use of stem cell therapies in vascular disease, the critical role of the vasculature in inflammation and immunity, modeling inherited vascular diseases with induced pluripotent stem cells, vascular biology of cancer, mechanisms of thrombosis and novel therapeutic anti-thrombotics. Our post-docs and PhD students are trained in using state-of-the art technologies such as intravital two-photon microscopy, super-resolution microscopy, protein engineering, high throughput small molecule screening or single cell transcriptomics. The training involves acquiring a range of skills from critical thinking and developing an innovative, testable hypothesis to deploying and utilizing relevant methods and technologies. We also offer opportunities to learn how to best communicate ideas and results through presentations and manuscripts. The success of our trainees is evident from their publication records in top tier journals and their current positions in academia and industry.

We have 40 preceptors participating in the training program who exhibit a breadth of scientific expertise ranging from basic cell biology to translational models of vascular disease. The faculty comprises a cohort of exceptionally talented mentors with a commitment to research training, collaboration, and developing careers of young investigators. These trainees and faculty meet regularly at the weekly vascular biology seminar as well as additional departmental seminars with invited speakers, many of whom are renowned leaders in the field of vascular biology. The program has several defining features that:
· contemporary biomedical research training must be underpinned by collaboration that can be local or international,
· research training is driven by fundamental ideas, and
· solving important scientific problems and research training should be such as to provide a variety of opportunities beyond the training phase.
The research training program provides opportunities for exposure to scientific leaders and role models and the intellectual environment of Chicago. It is our view that nurturing curiosity is a fundamental aspect of research training but that it also involves learning to ask important questions and becoming a well-rounded and humane individual.

Molecular and Cellular Pharmacology Training Program - University of Wisconsin-Madison

Kristin Cooper, MS
Program Coordinator
Molecular and Cellular Pharmacology
University of Wisconsin-Madison
Mail: Room 1005, 1111 Highland Ave
Office: L5/175
Madison, WI 53705
Phone: (608) 262-9826

Program Scope and Mission – Pharmacology is the knowledge of the biochemical and physiological actions of drugs, which act on cellular signaling pathways. The molecular basis of cellular signaling and its control by various drugs is a major aspect of modern pharmacology and this aspect is emphasized in the Molecular and Cellular Pharmacology Training Program. The majority of signal transduction pathways still await discovery or at least a thorough molecular characterization. Members of our program employ the whole spectrum of modern biochemical, cell and molecular biological, physiological, and pharmacological methods in a basic research-oriented scientific environment to unravel the many unsolved mysteries underlying cellular regulation and signaling. Certain research initiatives have a translational component, with the goal of applying basic discoveries to developing new therapeutic modalities.
Our program brings together an outstanding group of over 70 dedicated trainers with a focus on cellular signal transduction. Graduates of the program will be well prepared for a career in basic biomedical sciences in academia, industry, and more. We provide a unique training experience for young scientists who want to elucidate basic principles of cellular signal pathways. Detailed knowledge of these pathways is the most important prerequisite for the discovery of new drugs and the treatment of diseases. The members of the Molecular and Cellular Pharmacology Training Program invite you to examine the educational and research opportunities described on our website, and to consider joining this unique and exciting graduate program.

Postdoctoral Fellowship Training Program in Cardiovascular Outcomes Research - University of Missouri-Kansas City

John Spertus, MD, MPH
Missouri/Lauer Endowed Chair
Professor, University of Missouri-Kansas City
Clinical Director, Outcomes Research
Saint Luke’s Mid America Heart Institute
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Program Scope and Mission – Applications are invited for a 2-year postdoctoral training program in cardiovascular outcomes research to begin July 1, 2018. This T32 training program, funded by the National Heart Lung and Blood Institute to the University of Missouri-Kansas City (UMKC), is hosted by Saint Luke’s Mid America Heart Institute (SLMAHI) in close collaboration with the University of Kansas.

The Full-Time Training Program offers:
• Advanced seminars of specialized skills for Outcomes Research
• Opportunity to obtain an MS in Bioinformatics with an emphasis in Clinical Research for those without prior formal training in the field
• Multidisciplinary mentorship, individualized to meet the needs of each Fellow
• Hands-on research experiences with access to highly experienced statisticians and numerous databases including multicenter outcome registries (e.g., PREMIER, TRIUMPH, PORTRAIT, PRISM, OPEN CTO, OPTIMUM), clinical trial databases (e.g., PARTNER, FREEDOM, SYNTAX), national quality databases (e.g., ACC’s National Cardiovascular Data Registries, AHA’s National Registry of Cardiopulmonary Resuscitation) and publically available clinical trial and observational data sets.
• Salaried position based on NIH postdoctoral stipend scales
• Insurance benefits, vacation time, tuition (for MS coursework), and funds for travel expenses to professional conference(s)

University of Wisconsin Vascular Research Training Program

Program Director: Jon Matsumura, MD
Co-Program Director: Bo Liu, PhD
Program Coordinator: Sarah Pavao, Associate Administrative Program Specialist
Department of Surgery | University of Wisconsin School of Medicine and Public Health
K6/160 CSC | 600 Highland Avenue | Madison, WI 53792-1690
Phone: 608.262.0744
Fax: 608.252.0919
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Program Scope and Mission – The University of Wisconsin Vascular Surgery Research Training Program is a multidisciplinary and collaborative program that will co-train young physician/surgeons who have chosen to be vascular specialists, along with PhD scientists who have a research interest in vascular disease. This NIH-funded program provides trainees with multiple opportunities for research activities in vascular-related research disciplines in order to foster the development of knowledge, skill, and experience for success in the future academic careers of our trainees. Our goal is to accelerate the performance of basic, translational and clinical research for vascular disease by producing future surgeons, scientists and engineers who will meet the great need for innovation in treatments for the growing population of patients.

Understanding Cardiovascular Disease Mechanisms - The University of Cincinnati and Children’s Hospital

Jeffery D Molkentin, PHD
Children's Hospital Medical Center-Cincinnati
Office of Sponsored Programs
3333 Burnet Avenue, MLC #7030
Cincinnati, OH 45229
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Program Scope and Mission – The University of Cincinnati and Children’s Hospital is carrying on a proud tradition of excellence in cardiovascular research and mentorship, which began 35 years ago under Dr Arnold Schwartz as one of the longest training programs in cardiovascular. Our current collective 19 faculty has placed 297 of their past trainees into academics over their careers, 154 of whom have run, or currently run independent research programs. The overall scientific emphasis of our training program will continue to build from a basic platform of cardiovascular physiology, cell biology, biochemistry and pharmacology, but will also incorporate the latest approaches in the post genomic era, as well as incorporating clinical and translational approaches. The cardiovascular environment at Cincinnati Children's and the University of Cincinnati is considered one of the very best in the country, with 19 NIH funded faculty (some 49 NIH grants amongst them as PI status), 166 collaborative papers published in 10 years, and the very latest technologies and approaches with outstanding core support. The leadership consists of the co-PIs Drs. Evangelia Kranias and Jeffery D. Molkentin, both of whom have a long standing track record of working closely together (15 years), as well as having excellent mentorship credentials. The training grant funds 3 pre- and 3 postdoctoral trainees. Predocs are selected by the Internal Advisory Committee from a wide pool arising from departmental graduate programs, while postdoctoral candidates are selected based on being accepted into a mentor's laboratory and then passing the screening process by the Internal Advisory Committee and co-PIs. The training program also has an educational core where both pre-docs and post-docs take elective classes in cardiovascular biology, genetics, statistics, grant writing and ethics in research. More importantly, the cardiovascular training faculty at the University of Cincinnati and Children’s Hospital is one of the largest groups in the nation and they incorporate the very latest technologies in the pursuit of their scientific endeavors. Strengths include generation of transgenic and gene-targeted mice, as well as CRISPR-mediated mouse production, in the pursuit of understanding single gene function in complex cardiovascular diseases. Genetics are also employed and the program also has a strong clinical mentorship track for trainees interested in translational science.

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