Training Programs in Vascular Biology
Harvard-Longwood Research Training in Vascular Surgery – Beth Israel Deaconess Medical Center
Frank W. LoGerfo, M.D.
William McDermott Distinguished Professor of Surgery
Leena Pradhan-Nabzdyk, Ph.D., M.B.A.
Instructor in Surgery
Harvard Medical School
Beth Israel Deaconess Medical Center
Vascular Surgery Research-East Campus
330 Brookline Ave. Dana 805
Boston, MA 02215
Program Scope and Mission – The Harvard-Longwood Research Training in Vascular Surgery Program is designed to provide two years of intense basic research training in cardiovascular surgery for academic clinicians. The training program addresses the absence of adequate research training for cardiovascular surgeons as it applies to specific areas of clinical disease. This program is fully funded by the National Institutes of Health.Research training in molecular and cell biology, biomechanics, coagulation and thrombosis, and angiogenesis is provided with a focus on clinically relevant problems such as artherogenesis, intimal hyperplasia, prosthetic/host interactions and thrombosis. Trainees pursue a program of intense research design, ethics, statistics, and evaluation of published research. Trainees carry out their own research projects under the guidance of a faculty mentor. (They are not involved in any clinical activities unless research related.) Laboratory training can be supplemented by graduate level training at Harvard Medical School and Harvard’s Faculty of Arts and Sciences, with course selection complementing laboratory endeavors. Upon completion of the program, trainees are capable of independent research and possess the scientific and research background needed to obtain competitive grants; they have the abilities and knowledge necessary to provide translational expertise as they join medical school faculties.
The Multidisciplinary Training Grant (T32) in Cardiovascular Epidemiology - Boston University
Vasan Ramachandran, MD
Section of Preventive Medicine & Epidemiology| Department of Medicine
801 Mass Ave, 4th floor | Boston, MA 02118
Office: (617) 638-8009
Program Scope and Mission – The Multidisciplinary Training Grant (T32) in Cardiovascular Epidemiology is a training awarded by the National Heart, Lung, and Blood Institute. Trainees will focus their 2-year training on the epidemiology of cardiovascular disease such as coronary heart disease, stroke, heart failure and other forms of vascular disease, following one of the training pathways: statistical genetics and genomics, computational biology and bioinformatics, or clinical epidemiology.This position is a postdoctoral training opportunity paid a stipend, and the successful individual will be engaged in a temporary and a defined period (2-year) of mentored advanced training and professional development following completion of a doctoral degree program.
Training in Blood Diseases and Resources, T32 HL007501 - Boston University
Co-Directors Hematology Training Program:
Kevan Hartshorn - Director, Fellowship Program in Hematology/Oncology
Martin H Steinberg
Professor of Medicine, Pediatrics, Pathology and Laboratory Medicine
Boston University School of Medicine
72 E. Concord St.
Boston, MA 02118
Program Scope and Mission – The Boston University-Boston Medical Center Training Program in Blood Diseases and Resources” is a training program in hematology research that has been active at Boston Medical Center since 1980, currently supporting four pre-doctoral and four post-doctoral trainees/year. The objective of this training program is to provide training in hematology research to graduate students and PhD, MD, or MD, PhD post-doctoral trainees who work with any of 21 faculty. Our program faculty carry out hematology-related research in four areas: Hemoglobinopathies, Platelet and Thrombosis Biology, Hematopoiesis, and Lymphoid Cell Signaling and Immunopathology. We offer a rich research environment for trainees interested in hematology-related basic science, translational or clinical research projects. Among the research resources in hematoloic diseases available to trainees are the Boston University Center of Excellence in Sickle Cell Disease, the Center for Regenerative Medicine and the Amyloidosis Center. One of the strengths of the program is regular interaction at weekly Journal Clubs and Work Seminars between supported doctoral students, post-doctoral fellows and physicians carrying out their hematology fellowships. At the weekly Hematology Grand Rounds, talks are given by outside hematology researchers and such experts are made available to meet with trainees. Doctoral students enter the after having matriculated in variety of doctoral programs, including Biochemistry, Biology, Biostatistics, Microbiology, Molecular Medicine, Pathology and Pharmacology. A clinical research track is now offered to physicians who wish to obtain training in hematology-related clinical research.
NRSA Institutional Pre-doctoral Training Grant Training in Biomolecular Pharmacology - Boston University School of Medicine
David H. Farb
Richard Wainford, PhD, FAHA
Department of Pharmacology, Boston University
Program Scope and Mission – Of the 61 appointees to the Biomolecular Pharmacology Training Grant in the last 15 years, 87% earned the Ph.D. degree. The average time-to-degree has been 5.2 years for the 20 most recent graduates enrolled since September 2007. The current professional positions of graduates in the last 15 years reflect the diversity of opportunities available for Ph.D.s with expertise in pharmacology.There are three points of entry into the Biomolecular Pharmacology training program: PhD in Pharmacology, PhD in Biomedical Engineering, and PhD in Neuroscience. For more information visit the website. https://www.bumc.bu.edu/busm-pm/programs/
Training Program in Cardiovascular Biology, Pre-doctoral – Boston University School of Medicine
Director and Contact:
Katya Ravid, D.Sc.
Professor of Medicine and Biochemistry
700 Albany St Ctr for Adv Biomed Res
Phone: (617) 638-5053
Program Scope and Mission – Cardiovascular diseases represent the major causes of mortality and morbidity in the United States, and thus calls for major efforts in fundamental research. The training program, supported by the National Heart Lung and Blood Institute (NHLBI), provides a format for the training of future scientists who will devote time and efforts in developing the tools to study and control the disease.This program was initiated by Dr. Katya Ravid in 2003, inspired by Drs. Peter Brecher and the late Carl Apstein, prominent investigators and mentors in the field of Cardiovascular Biology. Training is offered to graduate students in topics related to cardiovascular disease, including atherosclerosis heart failure and hypertension, with application of disciplines such as, physiology, pharmacology, biochemistry, molecular biology and genetics. Trainees participate in various activities of the Whitaker Cardiovascular Institute (CVI) at our institute. The training faculty is affiliated with basic science departments and with the CVI. Each faculty has experience in teaching graduate courses, most have had numerous trainees that have gone on to hold academic positions, and all have at least one active grant from NIH. The program may be unique in that it provides an opportunity to train pre-doctoral fellows (PhD students and MD/PhD students) in translational and basic cardiovascular research in an academic setting in which considerable experience is available, where cutting-edge funded research in cardiovascular biology is ongoing, and where sensitivity to the need of graduate students is provided by an academic mentor approach.
Training Program in Cardiovascular Biology: Pre-Doctoral - Boston University School of Medicine
Executive Assistant: Robin MacDonald
BU Interdisciplinary Biomedical Research Office
Program Scope and Mission – Cardiovascular diseases represent the major causes of mortality and morbidity in the United States, and thus require major efforts in fundamental research. The training program, supported by the National Heart Lung and Blood Institute (NHLBI), provides a format for the training of future scientists who will devote time and efforts in developing the tools to study and control the disease. This program was initiated by Dr. Katya Ravid in 2003, inspired by Drs. Peter Brecher and the late Carl Apstein, prominent investigators and mentors in the field of Cardiovascular Biology. Training is offered to trainees in topics related to cardiovascular disease, including atherosclerosis heart failure and hypertension, with application of disciplines such as, physiology, pharmacology, biochemistry, molecular biology and genetics. The curriculum includes special courses in cardiovascular biology. Trainees participate in various activities of the Whitaker Cardiovascular Institute (CVI) at our institute. The training faculty is affiliated with basic science departments and with the CVI. There are strong research interactions between members of the training program. Each faculty has experience in teaching graduate courses, most have had numerous trainees that have gone on to hold academic positions, and all have at least one active grant from NIH. The program may be unique in that it provides an opportunity to train predoctoral fellows (PhD)and schools including Public Health, Cardiology, Medicine, Nursing, and the Morehouse School of Medicine. The program combines training in graduate degree programs in the Rollins School of Public Health with multidisciplinary research experiences working with top investigators in cardiovascular sciences from diverse disciplines, from basic sciences to epidemiology, cardiology, genetics, interventions, and health policy. The training follows a mentor-based model with formal didactic work in areas relevant to research in cardiovascular health inequalities (e.g., students and MD/PhD students) in translational and basic cardiovascular research in an academic setting in which considerable experience is available, where cutting-edge funded research in cardiovascular biology is ongoing, and where sensitivity to the need of graduate students is provided by an academic mentor approach.
Whitaker Cardiovascular Institute Training Program – Boston University School of Medicine
Victoria Bolotina, Ph.D.
Professor of Medicine, Physiology, and Biophysics
Whitaker Cardiovascular Institute
Program Scope and Mission – This program is unique, as it offers multidisciplinary state-of-the-art resources, advanced expertise of leading experts in the field, and professional guidance to a highly qualified and motivated group of post-doctoral fellows who want to pursue successful carriers in cardiovascular science. The program has developed a highly interactive research and training environment with successful collaborative initiatives which represent major fields of cardiovascular biology. Our mentors are the leading experts in the following fields:• Vascular Biology
• Diabetes and Obesity
• Basic Science
• Clinical Science (Translational Research)
• Regenerative Medicine
The Renal Section Training Program – Boston University School of Medicine
David J. Salant, M.D.
Chief, Section of Nephrology
Professor of Pathology and Laboratory Medicine
Dr. Craig Gordon
Director of Training Program in Nephrology
Boston Medical Center, Renal Section
650 Albany Street 5th Floor, Rm 504
Boston, MA 02118-2393
Phone: (617) 638-7330
Program Scope and Mission – The Renal Section offers comprehensive clinical and research training. The training programs are supervised by a large full-time staff, which currently includes 21 nephrologists and medical scientists, as well as several associate research training faculties. The size of the staff allows for broad coverage of the various clinical and research areas of nephrology. It also provides intensive supervision of fellows during both clinical and research training. Most fellows are physicians who have completed their training as the basis for a career in academic nephrology. For these individuals, a comprehensive fellowship program includes one year of clinical training in nephrology, usually but not necessarily taken first, and two or more years of research training. Other physician-trainees, anticipating a career in clinical nephrology, take the year of training in clinical nephrology followed by a year or more of training in clinical investigation.Training positions are also open to medical scientists with a Ph.D. degree who wish to receive post-doctoral fellowship training in aspects of physiology, molecular and cell biology, immunology and clinical research related to the kidney or its diseases. In addition, close ties have been established with basic scientists in other departments and sections of the Department of Medicine, which affords fellows the opportunity of training in molecular biology and basic immunology.
Endocrinology, Diabetes & Hypertension - Brigham & Women’s Hospital
Gordon H. Williams, MD
221 Longwood Avenue
Boston, MA 02115
Program Scope and Mission – A vibrant post doctoral Training Program in cardiovascular endocrinology and the cardiovascular and renal aspects of hypertension and diabetes mellitus has existed at Brigham and Women’s Hospital (BWH) (and its predecessor, Peter Bent Brigham Hospital) for over 50 years with an expansion a decade ago to include Morehouse School of Medicine. The Training Program’s continued success has been built on four premises: 1) dedicated trainers committed to the concept of long term effective mentoring; 2) creative mentees dedicated to establishing a lifelong career as biomedical scientists; 3) a pool of junior scientists committed to developing careers as mentors; 4) a dynamic and flexible group of knowledgeable scientists, external to the Core faculty and willing to serve as co-mentors, with expertise in disciplines critical for the career development of mentees. The expertise represented by our faculty members is far-reaching and diverse, including: pathophysiology of hypertension and of vascular diseases in diabetes mellitus, non-renal aspects of aldosterone action, pregnancy-induced hypertension, interventional nutrition, ion transport mechanisms, human genetics, regulation of gene expression, functional genomics, the molecular biology of the vasculature, the physiologic, molecular and cellular biology of veins and arteries, the effect of ethnicity and sex on vascular function and hypertension, regulation and function of natriuretic hormones, and regulation of the renal circulation and electrolyte handling. The disciplines represented are cardiology, endocrinology, nephrology, surgery, genetics, physiology, radiology, neurology, and cell and molecular biology. The techniques include human and intact animal cardiovascular function, ex vivo vascular function, immunology, development of genetically engineered mice, molecular and cell biology, quantitative assays for assessment of hormones and transduction and ionic factors. Finally, our program’s singular focus is the amalgamation of committed, established biomedical scientists with mature, highly motivated trainees to facilitate the mentees obtaining the tools and learning the concepts of biomedical science. Thus, the three-fold goal of this program is to provide a training experience that will allow the trainee to: create and perform independent research; obtain financial support for that research; and develop the tools necessary to be an effective mentor.
Training Program in Lung Science - Columbia University
Jahar Bhattacharya, MD, DPhil
Phone: (212) 305-7310
Fax: (212) 305-6701
Program Scope and Mission – The purpose of this T32 training program (Columbia University Training Program in Lung Science) is to provide an opportunity to promising post-doctoral individuals of exceptional quality to train in careers in pulmonary research. The program is limited to applicants who hold the MD, PhD or MD/PhD degrees and have a strong interest in research. The central features of the Program include intensive research with participating faculty members and didactic exposure to multiple courses in basic and translational science in pulmonology. Research areas span a wide range of pulmonary disciplines with centers of excellence in Acute Lung Injury (ALI), Lung Development, Asthma/COPD and Lung Vascular Biology. Expertise in biochemistry, cell biology, molecular biology, mouse genetics, biomechanics, and physiology are all well represented by the faculty. Highly experienced investigators provide expertise to fellows in a wide variety of subspecialties, including ALI, Infection and Asthma/COPD. Trainees are selected from a competitive pool of applicants. All trainees thus far have gone on to academic careers in pulmonology.
Irving Institute TL1 Training Program – Columbia University Medical Center
Wendy K. Chung, MD, PhD
Kennedy Family Professor of Pediatrics and Medicine
Sophia Li Ferry
Program Scope and Mission – The TRANSFORM TL1 Training Programs are intended to provide scholars with additional research training to prepare for a research career that can contribute in some meaningful way to understanding risk of disease, improving diagnosis and prevention, and tailoring treatment based on an individual’s variation in genes, environment, and/or lifestyle.With funding from the NIH CTSA award, the Irving Institute for Clinical and Translational Research seeks to promote high-quality research, enhance the integration of clinical and translational science, and deliver advancements more quickly to the patient community. An integral part of this effort is the TL1 Training Programs. We are recruiting applicants for the following programs:
• Post-Doctoral Fellows (2 year commitment to the program)
• Doctoral students (3 month commitment to the summer program) Eligibility (see website for more details):
• Must be a US Citizen or Permanent Resident
• Must have a Columbia appointment, position, or acceptance letter by the start of the award. We do not offer post-doc appointments nor do we accept students who are not formally enrolled in degree granting programs.
• Must have two interdisciplinary mentors. We can assist with connecting applicants to mentors, if needed. Here are some examples of potential research topics:
• Ecological momentary assessment of stress to identify personalized triggers for atrial fibrillation
• Using genetic profile of breast cancer tissue to target therapy
• N-of-1 trial to assess individualized treatment strategy for hypertension
• Apply machine learning to EHR data to predict individualized risk of hospital readmissions
• Integrating data from wearable devices with neighborhood walkability index to predict cardiovascular risk
Cardiology Fellowship Program – Icahn School of Medicine at Mount Sinai
Bruce D. Gelb, M.D.
Director Mindich Child Health and Development Institute
Professor of Pediatrics, Cardiology, and Genetics and Genomic Sciences
Program Scope and Mission – Recognizing that the future of basic cardiovascular research is in molecular approaches, Mount Sinai has made a major commitment towards developing one of the premier programs in the country. Established scientists in specific programs and centers perform cutting edge research illuminating cardiovascular biology and disease and train clinicians and scientists to become future leaders of these fields.The Cardiovascular Research Institute provides a home for a wide spectrum of investigation ranging from the most basic science to disease-focused and patient-based research. It also links faculty interested in cardiovascular biology and disease across Mount Sinai programs, departments, and campuses. The diversity of the faculty and its collaborative culture fosters a multidisciplinary approach to research problems and provides an important bridge between Mount Sinai's outstanding clinical and basic science departments. The research programs in Molecular and Cellular Cardiology have received substantial funding from the NIH, AHA and ACC. There are myriad opportunities for cardiology fellows to pursue basic and translational research. Fellows participating in the program have been involved in major research efforts in the areas of atherosclerosis, heart failure, transplant biology, cardiac excitation, ion channels, cardiomyopathy, and thrombosis. Fellows take courses in Molecular Biology, Cell Biology, Signal Transduction, Physiology and Neurobiology offered through the Graduate School Faculty of Mount Sinai. Fellows participate in journal clubs and seminars offered by the Brookdale Molecular Biology Center and the Molecular Medicine Program. Typically, fellows have presented the results of their work at the most prestigious international meetings of the American Heart Association, American College of Cardiology and American Federation for Medical Research (formerly AFCR).
Cardiovascular Disease Epidemiology Training Program – Johns Hopkins University School of Public Health
Director and Contact:
Josef Coresh, M.D.
George W. Comstock Professor
2024 E. Monument Street
Room 2-635, Suite 2-600
Baltimore, Maryland 21287
Program Scope and Mission – Established in 1975, the Cardiovascular Disease Epidemiology Training Program focuses on interdisciplinary training on the epidemiology of the leading cause of death in the United States. The program integrates knowledge on all aspects of cardiovascular disease: biology, behavior, treatment and prevention. Training emphasizes active participation in research and translational epidemiology using a collaborative approach, which is enhanced by the close relationships between the Department of Epidemiology and the clinical departments of the Johns Hopkins School of Medicine at the Johns Hopkins Hospital. A number of large ongoing cohort studies and clinical trials provide a rich environment for the conduct of research. The main didactic course focuses on risk factors for cardiovascular disease and strategies for prevention. Seminar-style courses offer a more in-depth understanding of disease pathophysiology and clinical management.The strengths of the program include the existing depth of interest and expertise in cardiovascular disease epidemiology at the Johns Hopkins Medical Institutions, as well as the enthusiasm, commitment, and experience in training and mentorship of the Program Director (Dr. Josef Coresh), Program Co-director (Dr. Elizabeth Selvin) and program faculty. Many trainees are based in the Welch Center for Prevention, Epidemiology and Clinical Research and are mentored by individuals active in both population-based and clinical research. Among other outstanding collaborations, the program benefits from close ties with the Johns Hopkins University Divisions of General Internal Medicine, Cardiology and Endocrinology.
Training Program in the Molecular Bases of Eye Diseases - Schepens Eye Research Institute, Boston, MA
Dr. Patricia D’Amore, PhD, MBA, FARVO
Department of Ophthalmology at Harvard Medical School
Program Scope and Mission – The Training Program in the Molecular Bases of Eye Diseases (MBED) is an ongoing postdoctoral training program in the Department of Ophthalmology at Harvard Medical School (HMS) that is aimed at attracting and mentoring talented and motivated basic scientist trainees in the field of vision research. The program includes 40 faculty members who represent a wide choice of research interests and expertise to the trainees in the program. The mentors represent a diversity of relevant disciplines including development, ocular immunology, vascular biology, neurobiology, regenerative medicine, gene therapy, growth factor biology, to name a few. In addition, the research faculty are investigating a number of important ocular pathologies such as age related macular degeneration, glaucoma, retinopathy of prematurity, retinal degenerations, corneal inflammation, wound healing, dry eye and corneal transplantation. This diversity provides a wide selection of training opportunities. The training program seeks to train scientists who will use a range of disciplines to investigate, the cause of blinding diseases with the goal of identifying methods for earlier diagnosis, more effective treatments, means for prevention and eventually to develop cures.
Since the initiation of the program in 1997, the program has trained and mentored 78 trainees, many of who continue in the field of vision research and whose achievements are reflected in their publications and presentation record. The goal of the MBED training program is to provide trainees with expertise in molecular approaches and models as well as an understanding of and the ability to recognize the important clinical and basic research questions facing ophthalmology. The commitment of the faculty to the success of their trainees is evidenced by the quality and success of resulting trainees. The location of the affiliate institutions in Boston provides an outstanding research environment with access to excellent facilities and resources. The program encompasses all aspects of training required to produce an independent and successful vision researcher including: full-time research, didactic courses and mentoring. These are all aimed at educating well qualified trainees in knowledge and understanding of the basic and clinical principles that are key to identifying and solving important ophthalmic problems, instruction in grant and manuscript writing and review as well as presentation skills, and training in the responsible conduct of research.
Transdisciplinary Training in Cardiovascular Research – University of Massachusetts Medical School
Catarina I. Kiefe, Ph.D., M.D.
Chair and Professor
University of Massachusetts Medical School
Program Scope and Mission – The University of Massachusetts Medical School (UMMS) has a cardiovascular T32 training grant entitled "Transdisciplinary Training in Cardiovascular Research" under the direction and senior leadership of Drs. Catarina Kiefe and John Keaney. The program represents a wonderful opportunity for the institution to promote the entire spectrum (T0 – T2+) of cardiovascular research on the UMMS campus. A call has been issued to request applications from trainees who wish to become part of this exciting program at the post-doctoral level. New trainees will join four other current trainees in the program.Eligibility: Please see http://grants.nih.gov/grants/guide/pa-files/PA-14-015.html Applicants must show evidence of high academic performance in the sciences and commitment to a career as an independent researcher. Post-doctoral candidates must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, DrPH, DNSc, PharmD, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution. By the time of the award, the individual must be a citizen or a non-citizen national of the United States or have been lawfully admitted for permanent residence (i.e., possess a currently valid Permanent Resident Card USCIS Form I-551, or other legal verification of such status). This fellowship program may not be used to support the clinical years of residency training. However, these awards are appropriate for the research fellowship years of a residency program. Research clinicians must devote full-time to their proposed research training and confine clinical duties to those activities that are part of the research training program.
Predoctoral Training In Pharmacological Sciences - University of Pittsburgh, School of Medicine
Patrick J. Pagano, Ph.D., FAHA
Professor & Vice-Chair for Graduate Education
Department of Pharmacology & Chemical Biology
Molecular Pharmacology Program
Vascular Medicine Institute
Ms. Shannon Granahan
Coordinator, Molecular Pharmacology Program
BST Starzl Tower: W1340
University of Pittsburgh School of Medicine
Pittsburgh, PA 15261
Program Scope and Mission – Molecular Pharmacology is a basic science into the molecular exploration of fundamental cellular processes in normal physiology and in disease. The Molecular Pharmacology Training Program (MPTP) of the University of Pittsburgh is a comprehensive, interdisciplinary program that provides research training in the basic and translational aspects of Pharmacology. The MPTP offers formal training through coursework and provides research opportunities individually tailored to suit each student. The program is outstanding in its long-term innovations in training students to be critical thinkers and leaders in their career track of choice as well as to complete their dissertation in a timely manner. The Pharmacology Training Program T32 provides up to 2-years of support in a wide range of disciplines ranging from cardiovascular disease to cancer therapy, neuropharmacology and GPCR receptor signaling.
Translational Research And Entrepreneurship In Pulmonary Vascular Biology - The University of Pittsburgh
Mark Gladwin, MD
Vascular Medicine Institute
University of Pittsburgh
Department of Medicine
Division of Cardiology, E1150 BST
200 Lothrop Street
Pittsburgh, PA 15261
Program Scope and Mission – Biomedical investigators are experiencing a limitation in their collective ability to translate the remarkable basic science discoveries of the current era into the clinical arena—a divide appropriately termed “the valley of death.” In our first cycle of funding, we developed a novel training program in bench-to-bedside research methodology designed to train the next generation of clinical and basic researchers in translational approaches to pulmonary vascular biology and medicine. In an effort to address the increasing pressure from the NIH, political leaders, and the public to translate basic discovery into therapeutic applications that positively change lives, we have recently extended the scope of our program to incorporate entrepreneurial training, including:
1) development of a novel joint University of Pittsburgh (ranked #5 in NIH funding)-Carnegie Mellon University MBA Program (ranked #1 in part-time programs) in Entrepreneurship;
2) elective rotations focused on commercialization of biotechnology; and
3) an expanded faculty that includes translational scientist-entrepreneurs.
Training Program in Imaging Sciences in Translational Cardiovascular Research - The University of Pittsburgh
Flordeliza Villanueva, MD.
Department of Medicine
Division of Cardiology, E1150 BST
200 Lothrop Street
Pittsburgh, PA 15261
Program Scope and Mission – Capabilities for biologic imaging at all levels--spanning molecules to man--have evolved to an unprecedented level of sophistication such that we can now visualize anatomic, functional, cellular, and molecular processes heretofore invisible, opening exciting new opportunities to study disease pathogenesis . In order for this ever- growing capacity to "see," to facilitate bedside translation of scientific discoveries, images must understand what questions are important in biomedical research, and conversely, biomedical scientists must be fluent in the imaging technologies that could revolutionize their work. However, there is a paucity of scientists who can comfortably commute between the spheres of imaging science and biomedical research, resulting in a "disconnect" that stymies what should otherwise be a powerful, bi-directionally facilitative, relationship between imaging science and translational research. To close this chasm, our new T32 Program employs an innovative educational paradigm to train future clinical and basic researchers in a broad spectrum of cutting edge, multimodality imaging platforms as they pursue hypothesis-driven research, with a specific emphasis on translational cardiovascular research. While there are T32s focused on traditional cardiovascular imaging tools (e.g., MRI, SPECT, Echo), to our knowledge, no training program comprehensively integrates biological imaging within translational biological and physical sciences. Our post-doctoral trainees (MD or PhD) will acquire "core competencies" in imaging methods spanning molecular to whole organism ("imaging tool kit") and in the conduct of translational research spanning basic to population levels ("translational tool kit') -- accomplished through a co-mentorship structure, with each trainee having one mentor from the imaging sciences, and another from the biomedical science arena. Our training strategy is structured around Individualized Development Plans that emphasize quantifiable outcomes based on abstract presentations, publications, pursuit of career development grants, completion of didactic courses, or completion of Masters Programs.
The Director, Dr. Villanueva, is a cardiologist, imaging specialist, and translational researcher with extensive mentoring experience. In actualizing the reciprocal relationship between imaging sciences and biomedical research espoused by this T32, she has been at the forefront of molecular probe and ultrasound technology development for molecular imaging and therapeutics. Our Training Committee comprises the Director and 3 co-Directors with expertise in basic, translational, and clinical research and training. Our 15 Imaging Faculty embody the full gamut of state-of-the-art imaging technologies, and 16 Biomedical Science Faculty offer multiple levels of translational research topics in cardiovascular medicine. The Program is enhanced by institutional endowments to Cardiology and the Heart, Lung, Blood, and Vascular Medicine Institute (VMI), a rich infrastructure from the Clinical Sciences Translational Institute and Center for Ultrasound Molecular Imaging and Therapeutics, VMI Cores, and interactions with other institutional translational T32s.
Training in Multi-Modality Molecular and Translational Cardiovascular Imaging - Yale University School of Medicine
Albert J. Sinusas, MD
Yale University School of Medicine
Section of Cardiovascular Medicine, DANA-3
P.O. Box 208017
New Haven, CT 06520-8017
Program Scope and Mission – The training program is focused on providing multi-disciplinary multi-modality training in molecular and translational cardiovascular imaging for highly qualified fellows holding either a MD or/and PhD, in preparation for academic careers as independent investigators in the highly clinically relevant field of cardiovascular imaging. Post-doctoral fellowship training will be 2-3 years in duration. Currently four fellowship slots are available, although this will be expanded to six. There are three primary research focuses in the post-doctoral training, 1) cardiovascular molecular imaging, 2) cardiovascular imaging technologies and analyses, and 3) translational cardiovascular imaging. Applicants will have full access to resources available through the Yale Translational Research Imaging Center (Y-TRIC), including: small and large animal surgical suite, state-of-the-art digital fluoroscopy suite, 3D ultrasound, novel hybrid CZT SPECT 64-slice CT, microSPECT/CT, microCT, and optical imaging, along with other institutional resources, including; PET/CT, and MRI. Participation in ongoing NIH funded projects. Applications are encouraged from clinical, engineering, and basic science departments. Each trainee is assigned a basic and clinical mentor, and participates in group projects, and weekly seminar series. The goal is to train individuals to work in a multi-disciplinary research environment. Applicants are encouraged to visit our website: http://y-tric.yale.edu/.
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