Training Programs in Vascular Biology
Training to Improve Cardiovascular Therapies – Medical University of South Carolina
Dr. Donald Menick, Ph.D.
Director, Gazes Cardiac Research Institute
Professor of Medicine
Professor of Biochemistry & Molecular Biology
Director, Molecular & Cellular Biology & Pathology Program
Dr. Donald Menick, Ph.D.
Department of Medicine, Division of Cardiology
Medical University of South Carolina
Gazes Cardiac Research Institute
114 Doughty Street, Room 203
Charleston, SC 29403
Program Scope and Mission – Research at the Medical University of South Carolina (MUSC) has rapidly developed over the past 25 years and cardiovascular biology has been a major focus of resource commitment. For FY2011 MUSC investigators received more than $12.7 million of research funding from the NHLBI alone. Since the beginning of this training program in 1977, there has been and continues to be a strong emphasis on the molecular and structural aspects of the entities involved in cellular dysfunction in cardiovascular disease. MUSC provides an exciting environment for creative, committed investigators and trainees interested in cardiovascular function in health and disease.Postdoctoral and predoctoral positions are supported by the National Institute of Heart, Lung and Blood training grant "Training to Improve Cardiovascular Therapies". Our objective is the training of promising new scientists with backgrounds in physical, chemical and biomedical sciences in mechanisms of cardiovascular diseases and the experimental strategies and technologies necessary for the development of novel molecular therapeutics targeting these diseases. Our aim is to produce outstanding investigators with broad insight into cardiovascular biology and dysfunction capable of making significant contributions to cardiovascular research. Faculty in the training program come from five broad research areas: 1) Molecular basis of cardiovascular development, 2) Mechanisms of cardiovascular development, 3) Cardiac stem cells and regenerative medicine and bioengineering, 4) Cell signaling, and 5) Proteomics. Our faculty is highly interactive in both predoctoral and postdoctoral training, and our postdoctoral students benefit in many ways from an organized graduate program in cardiovascular biology.
NHLBI Integrated Biostatistical Training Program for CVD Research– North Carolina State University
Dr. Marie Davidian, Ph.D.
J. Stuart Hunter Distinguished Professor
Program Co-Director, NHLBI Integrated Biostatistical Training Program for CVD Research
Dr. Marie Davidian
Department of Statistics
Program Scope and Mission – The shortage of skilled biostatisticians equipped to address emerging challenges in this exciting new era of CVD research calls for training that formally integrates (i) in-depth experience in collaboration in a multidisciplinary environment, (ii) mastery of the theoretical underpinnings of statistics required for valid application of sophisticated biostatistical techniques and research on development of new methodology, and (iii) emphasis on communication and leadership skills. The program capitalizes on the long-standing partnership between NCSU and Duke, which provides trainees with the opportunity for outstanding theory and methods training and to work with internationally-known researchers at the forefront of CVD research. Trainees will develop all of these skills through interaction with faculty at both universities, who themselves have a history of inter-institutional collaboration and research and who have extensive experience in training and mentoring.The training involves formal coursework in the student's home department on foundational statistical theory, including probability, inference, linear and other statistical models, measure theory and advanced probability, and advanced statistical inference; and on statistical methods, including clinical trial design/analysis, longitudinal data analysis, survival analysis, epidemiology, causal inference, machine learning, and high-dimensional data analysis; and exposure at DCRI to fundamental aspects of CVD medicine, working with large, complex biomedical data, and research responsibility and ethics considerations. There is also extensive formal and experiential training in communication and leadership skills at both institutions. Trainees are introduced to DCRI CVD research gradually and will evolve over their tenures to holding substantial collaborative apprenticeships in which they are fully integrated as functioning members of DCRI project teams. The apprenticeships will provide trainees with extensive working knowledge of CVD research, the opportunity to develop collaborative skills, and the recognition of how new biostatistical methods development follows from challenges encountered in the collaborative context. This last point will be emphasized through mechanisms under which statistical methodological challenges arising in trainees' apprenticeships will lead to doctoral dissertation research in biostatistics.
Training in Botanical Approaches to Combat Metabolic Syndrome - Pennington Biomedical Research Center
Director and Contact:
Phillip J. Brantley, PhD
Associate Executive Director For Scientific Education
Pennington Biomedical Research Center/LSU
6400 Perkins Road
Baton Rouge, Louisiana 70808-4124
Program Scope and Mission – Pennington Biomedical Research Center in Baton Rouge, Louisiana invites applications for postdoctoral fellowships on their NCCIH Institutional Training. We are seeking MDs or PhDs with biomedical research experience who are interested in conducting basic research into obesity, diabetes, and the use of botanicals to attenuate metabolic syndrome. Eligible Applicants must be a US citizen or green card holder. Evidence of motivation and skills in scientific writing such as publications and grant experience are highly desirable. Fellowships provide up to three years of funding, and include didactic instruction and mentored laboratory based training necessary to establish an independent research career. http://www.pbrc.edu/training-and-education/postdocs/botanical-approaches-to-combat-metabolic-syndrome/
Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease - University of Kentucky
Nancy R Webb, PhD
T32 Program Director
Department of Pharmacology and Nutritional Sciences
Director, Division of Nutritional Sciences
535 Wethington Health Sciences Building
Lexington, KY 40536-0200
Phone: (859) 218-1385
Program Scope and Mission – An NIH-funded T32 training grant entitled “Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease” is housed in the Department of Pharmacology and Nutritional Sciences, Division of Nutritional Sciences at the University of Kentucky. The training grant seeks to prepare biomedical scientists for academic careers in research focused on pharmacological and nutritional approaches to prevent and treat metabolic-based disorders. The training faculty come from 8 different departments in 4 Colleges across the University of Kentucky campus. They have expertise in the four theme areas of the training grant: obesity/diabetes, cardiovascular disease, cancer, and neuroscience/aging.
Clinical Scholars in Cardiovascular Science - University of Kentucky College of Medicine
Susan Smyth, M.D., Ph.D.
Chief, Division of Cardiovascular Medicine
Linda and Jack Gill Heart and Vascular Institute
Director, MD/PhD Program
326 CTW Building 900
900 south Limestone Street
Lexington, Kentucky 40536-0200
Website: Clinical Scholars in Cardiovascular Science
Leigh Ann Callahan, M.D.
Program Scope and Mission – The University of Kentucky Training Program for Clinical Scholars in Cardiovascular Science is designed to prepare exceptional clinical and postdoctoral fellows to assume leadership positions directing multidisciplinary research in the field of cardiovascular medicine. In the last several years, as a consequence of substantial institutional commitment, we have assembled an integrated approach of incorporating basic, translational and clinical cardiovascular science in four concentrations: Thrombosis and Inflammation; Atherosclerosis and Aneurysm; Cardiac Hypertrophy and Heart Failure; and Vascular Cell Response to Stress. Our cardiovascular science strengths to provide a unique multidisciplinary training program that unites trainees across the disciplines of Medicine, Nursing, and Pharmacy with the goal of increasing the pipeline of clinical investigators who will bridge the gap between basic science advances and their application to clinical medicine. Specifically, we aim to:1) To provide a rigorous and solid research education in the basic sciences related to cardiovascular research
2) To prepare new researchers for translational and clinical science in a highly interdisciplinary environment
3) To provide training in the efficient and ethical conduct of high quality laboratory management and science
4) To create an environment that incubates fellows and mentors with an innovative and nurturing structure of interlaced mentoring teams
The program is available to M.D., M.D./Ph.D., R.N./Ph.D., Pharm.D., and Ph.D.s with clinical emphasis who are at the early post-doctoral stage of their careers. Upon completion of the program, we anticipate that the trainees will have the experience and capabilities necessary to initiate an independent career as clinical investigator.
Genetic Epidemiology of Heart, Lung, and Blood Traits Training Grant - University of North Carolina, Chapel Hill
Kari North, PhD
Professor and Program Director
Department of Epidemiology
University of North Carolina
137 East franklin Street Suite 306
Chapel Hill, NC 27599
Program Scope and Mission – Human genome studies are providing fresh insights into heart, lung, and blood (HLB) traits, with opportunities for translation of research findings to clinical and community settings for disease prevention and health promotion. Yet, there remain an insufficient number of HLB genetic epidemiologists who can design and implement multidisciplinary HLB genetic epidemiology research that combines technological advances in genome measurement with cutting-edge statistical tools to advance understanding of the genomic basis of HLB traits and associated diseases in the most-burdened populations.The Genetic Epidemiology of Heart, Lung, and Blood Traits (or GenHLB) Training Grant responds to these research gaps by providing interdisciplinary, integrated, and comprehensive instruction in the genetic epidemiology of HLB traits from an outstanding team of research mentors with expertise spanning four proposed training dimensions: HLB genetic epidemiology; computation/methods; `OMICs; and culture, diversity, and disparities. The Training Program will encompass formal didactics based on an individual development plan; tailored mentorship; research experiences in two training dimensions; presentations; manuscript and grant preparation; research seminars and colloquia; and instruction in the responsible conduct of research. The GenHLB training program also will include careful evaluation of the quality and effectiveness of the Training Program, ensuring that fellows achieve the competencies and skills necessary for success as future HLB genetic epidemiology research leaders.
The five-year program aims to support four (two pre-doctoral and two postdoctoral) fellows at initiation, increasing to six (three pre-doctoral and three postdoctoral) fellows in year 03. Among the postdoctoral fellows, prior expertise in epidemiology, human genetics, biostatistics, bioinformatics, computational biology, medicine, and applied mathematics will be sought. Pre-doctoral fellows will be required to pursue a doctoral degree in epidemiology, specializing in HLB genetic epidemiology. Our selection of internationally known research mentors with established research collaborations, unique and multidisciplinary training environment, and unparalleled research opportunities make us exceptionally well-positioned to lead this novel training program and develop the next generation of genetic epidemiology leaders who are well-equipped to investigate the genetic underpinnings of HLB traits and associated diseases.
Predoctoral Training Program in Integrative Vascular Biology - University of North Carolina - McAllister Heart Institute
Christopher Mack, Director
Associate Professor of Pathology
University of North Carolina
111 Mason Farm Road
Suite 2341 MBRB
Chapel Hill, NC 27599
Contacts & Grants Facilitator
Program Scope and Mission – In response to the demands of the post-genomic era, we established the Integrative Vascular Biology (IVB) Pre-doctoral Training Program at the University of North Carolina in 2002 to promote a collaborative interdisciplinary training environment for pre-doctoral students in the cardiovascular field. The IVB Program was founded on the breadth and depth of the cardiovascular research faculty at UNC and institutional strengths in genetic model systems, state of the art cell biology and imaging, high throughput genomic and proteomic analyses, and computational biology. The overall goal of the IVB Program is to provide Trainees with the interdisciplinary and collaborative skills necessary to extend their thesis work into new, innovative, and productive directions. Our primary training faculty are drawn from 12 UNC departments and have specific expertise in heart and blood vessel development, thrombosis and hemostasis, the mechanisms that contribute to atherosclerosis, and the pathophysiology and treatment of myocardial ischemic disease. By requiring trainees to collaborate with secondary mentors outside of their Field, Department, and/or Institution, the program teaches students to apply molecular, cellular, genetic, and computational approaches to pathological and physiological questions in cell, organ, and whole animal systems; to merge hypothesis- and discovery-based research; to develop high-throughput approaches in cardiovascular models, and to translate their work to clinical settings. Trainees are exposed to the latest concepts in cardiovascular biology by enrolling in advanced paper-based courses specifically designed for UNC's Graduate Certificate Program In Cardiovascular Science, by attending formal cardiovascular seminars by inside and outside speakers, and by participating in a bi-weekly student-led discussion group. To enhance the skills necessary for effective collaboration and career advancement, Trainees attend program workshops on grant writing, career development, and scientific rigor and responsibility, and they present their data formally at the annual IVB Research Symposium, a trainee-organized event that draws over 120 cardiovascular researchers from the greater Chapel Hill area. In summary, with an outstanding history in cardiovascular research, a strong, well-funded group of investigators centered around the McAllister Heart Institute, a structured academic program in Cardiovascular Science, and institutional excellence in genetic model systems, cell biology, high throughput sequencing, and computational biology, the UNC Integrative Vascular Biology Program offers an outstanding environment for multidisciplinary training of pre-doctoral students. For more information, please contact program Director Christopher Mack.
Pathobiology Of Occlusive Vascular Disease – University of Texas Health Center, San Antonio, TX
Director and Contact:
Dr. James D. Stockand, PhD
University of Texas Health Science Center
Department of Cellular and Integrative Physiology -7756
7703 Floyd Curl Drive, MSK 7756
San Antonio, TX 78229
Program Scope and Mission – Cardiovascular disease complications remain the major leading cause of death and disability in the United States and other developed countries. While lifestyle clearly contributes to the development of cardiovascular disease, it has not proven realistic to expect resolution of major morbidities (and attenuate costs) simply on the basis of changes in lifestyle. Consequently, biomedical science must continue to address improvements in the prevention, diagnosis and treatment of the widespread and devastating complications of cardiovascular disease. To achieve this goal, a cadre of well-trained, multidisciplinary scientists, capable of working in investigative teams, is required. This postdoctoral research training program enables the continued achievement of excellence in research training in cardiovascular pathobiology by preparing new investigators with the necessary competencies and breadth of expertise needed for future biomedical research.
This is a multi-disciplinary postdoctoral research training program in cardiovascular science that annually supports six doctoral graduate fellows in medicine, dentistry, veterinary medicine, or the basic biomedical sciences. Program faculty are distributed among twelve academic departments at the University of Texas Health Science Center at San Antonio, and two departments at nearby sister institutions, the University of Texas at San Antonio and the Southwest National Primate Research Center.
Lung Biology and Disease Postdoctoral Training Program (T32)- University of Texas Southwestern Medical Center
Lance Terada, MD
Professor and Chief
Pulmonary and Critical Care
Philip Shaul, MD
Vice Chair for Research
Professor and Chief
Pulmonary and Vascular Biology
Lance Terada, MD
Program Scope and Mission – This program provides structured research training opportunities at the postdoctoral level with support for two years of training. The proposal is born out of a collaborative effort between divisions within the Pediatric and Internal Medicine departments involved in lung and vascular research at this institute, and is thus interdepartmental at its core. Our training faculty consist of experienced investigators representing 16 different clinical and basic science departments and centers, forming a solid, diverse training force, organized into four thematic tracks: 1) Pulmonary vascular disease; 2) Interstitial lung diseases; 3) Lung epithelial cell and differentiation disorders; and 4) Immunity/Inflammation/Sepsis. Besides mentor-based teaching, trainees will receive a comprehensive track- and project-specific didactic curriculum. Both clinical and basic science trainees will be guided by an individualized advisory committee that has both basic and clinical science mentors, to broaden the trainee’s perspective and facilitate bench to bedside thinking. Emphasis will be placed on maintenance of project focus, creative experimental design, state of the art technology, and careful early career guidance.
T32 Kidney Disease and Inflammation - University of Virginia
Director and Contact:
Mark D. Okusa, MD
1300 Jefferson Park Avenue
West Complex, Room 5097B
University of Virginia Health System
Charlottesville, VA 22908–0133
Program Scope and Mission – Kidney disease is a major health problem for both adults and children. Renal diseases of various etiologies continue to grow at a rate of epidemic proportions. Furthermore there is a diminishing “pipeline” of nephrology trainees leading to a lack of new discoveries, cures and clinical trials in the kidney research arena. It is imperative that we meet this challenge and ensure the training of a new cadre of outstanding investigators in kidney-related research. The goals of the program are to identify promising candidates and train them for careers in academic nephrology. We have assembled an exemplary team of clinician and basic science investigators with an outstanding track record of mentorship from various Departments and Centers including: Medicine, Pediatrics, the Pediatric Center of Excellence in Nephrology, Pharmacology, Microbiology, Molecular Physiology and Biophysics, Biomedical Engineering, the Cardiovascular Research Center, Surgery, the Beirne Carter Center of Immunology and Public Health Sciences. The basic/translational faculty laboratories offer research experience that links kidney development, cell fate, and disease with inflammation. The program provides training and didactic instruction in fundamental and cutting-edge methodologies, including novel molecular, cellular, transgenic and imaging technologies, as well as immunology, functional genomics and novel imaging technologies. The patient- oriented clinical research program provides training in clinical investigation, epidemiology, biostatistics and human genetics. Three new mentors in genetic susceptibility to kidney disease and disease progression have been recruited. Adult and Pediatric Nephrology trainees with M.D. degrees will pursue a program consisting of 1 year of clinical training, which is not supported by the grant, and 2-3 years of research training funded by this application. PhD applicants will be required to have prior research experience and outstanding references. Each of the thirty-four mentors/co-mentors has a track record of mentorship and is an expert in one or more core areas that pertain to kidney development and disease and inflammation including: kidney development and disease pathogenesis, diabetes/vascular disease, cell signaling, leukocyte biology and patient-oriented research/genetic epidemiology. All trainees will be required to attend regular seminars, journal clubs and specific courses addressing research methodologies, experimental design, research integrity, ethics and faculty development, in addition to. Newly designed translational programs are aimed to link clinical disease with basic science. They will be expected to design, conduct, and analyze experiments with progressive independence in our new, modern, and well-equipped laboratories. We value and encourage applicants from diverse academic and ethnic backgrounds. It is the goal of the mentored training program that its graduates attain a strong foundation in translational biomedical research and be among a new generation of academic nephrologists and renal investigators who will make significant contributions in addressing the growing problem of kidney disease in the adult and pediatric populations.
Cardiovascular Research Training Program - University of Virginia, Charlottesville
Gary K. Owens Ph.D.
Programs Administrator/Administrative Generalist
Robert M. Berne Cardiovascular Research Center
415 Lane Road (MR5) PO Box 801394
Charlottesville, Va. 22908
Program Scope and Mission – Despite decades of research there are still fundamental gaps in our knowledge of the underlying mechanisms that contribute to development and progression of most cardiovascular diseases (CVD), as well as the end stage clinical consequences of these diseases and how to better treat or prevent them. Indeed, CVD remains the leading cause of death worldwide. A central premise of our NIH T32 cardiovascular (CV) research training program (CVTP) is that these diseases are extremely complex, and that rigorous study of them requires trainees to have a strong foundation of knowledge of basic CV physiology, developmental biology, genetics, genomics, bioinformatics, epigenetics, pathology, systems biology, biomedical engineering, and many other disciplines. A major strength of our CVTP is that we have >50 outstanding clinical, translational, and basic science mentors representing all of these areas, and we have built a unique training program over the past three decades that integrates mentoring talents into producing the best trained cardiovascular scientists possible. Our goal is to provide pre-doctoral and post-doctoral trainees the necessary knowledge, intellectual capabilities, technical skills, and problem-solving abilities to conduct outstanding state-of-the-art CV research employing a wide range of powerful and innovative approaches.
The program is led by Dr. Gary K. Owens and two talented Associate Directors Drs. Brant Isakson and Shayn Peirce-Cottler who are exceptional CV researchers and mentors. Pre-doctoral trainees are selected from a large pool of outstanding trainees initially recruited into an umbrella biomedical sciences (BIMS) graduate program http://bims.virginia.edu/ or the UVA MD/PhD (NIH MST) Program https://mstp.med.virginia.edu/, whereas post-doctoral candidates are largely recruited by individual mentor labs or from one of several clinical residency-fellowship programs. After completing a highly innovative BIMS 6000 core course in integrated biology in year 01, CVTP pre-doctoral trainees take elective modular courses that are customized based on their interests and degree program. They also complete three lab rotations to aid in selection of a mentor. Only trainees who have already selected a CVTP mentor are eligible for appointment to our NIH T32 training grant. All trainees are required to take our signature CVTP advanced courses including BIMS 8052-3 (Advanced Vascular Biology) and BIMS 8064 (a trainee-run Careers/Professionalism Course), and are also required to attend our weekly research seminars, monthly research in progress sessions, bi-annual research retreats, and to complete biomedical ethics training. The CVTP also has an exceptional grant writing program including an annual workshop and approximately 20 annual grant brewing sessions.
There are many indices of the success of this program including CVTG trainees: 1) publishing many high impact first author papers including in some of the highest rated biomedical journals such as Nature, Nature Medicine, and Circulation Research; 2) having a >50% success rate in securing extramural fellowships upon first submission; 3) securing high quality post-doctoral, or faculty/leadership positions, at major academic medical centers, in the pharmaceutical industry, or with biotechnology companies; and 4) making extraordinary contributions advancing our understanding of the cardiovascular system, as well as developing better ways to treat or prevent CVD.
T32 Resident Lung Transplant Research Training Program – University of Virginia School of Medicine, Charlottesville, VA
Irving L. Kron, M.D.
Professor and Chair of Surgery
Division of Thoracic and Cardiovascular Surgery
Tony Herring, Laboratory Manager
P.O. Box 801359
Bldg MR4, Rm 3116
409 Lane Road
Charlottesville, VA 22908
Office: 434-924-9297 Fax: 434-924-1218
Victor E. Laubach, PhD
Professor of Surgery
Office: 434-924-2927 Fax: 434-924-1218
Program Scope and Mission – Our TCV Surgery Research Training Program has been continuously funded since 2000 by an NIH T32 Training award with Dr. Irving Kron as the Principle Investigator. This training program provides collaboration between basic scientists and surgical faculty to train academic cardiothoracic surgeons. The main objective of our program is to provide surgery residents with hypothesis-driven research training in laboratory or clinical research in order to foster their development into independent academic translational researchers. Translational research defines the area of overlap between basic and clinical studies, where new therapies, interventions, assays, etc. are brought out of the laboratory for human benefit. The primary discipline which our program focuses on is translational research into vascular and end-organ function following transplantation or surgery.
Cardiovascular Imaging Fellowship Program – University of Virginia School of Medicine, Charlottesville, VA
Christopher M. Kramer, M.D.
Ruth C. Heede Professor in Cardiology
Director, Cardiovascular Imaging Center
Cardiovascular Imaging Fellowship Coordinator
UVA Division of Cardiovascular Medicine
1215 Lee Street, Room 2772
PO Box 800662
Charlottesville, VA 22908
Program Scope and Mission – UVA’s advanced fellowship in cardiovascular imaging trains fellows in the use of cutting-edge technology that in turn facilitates a better understanding of the mechanisms of heart disease and of cardiac physiology and pathophysiology.Specific program goals include:
- providing competence in technical aspects of imaging;
- providing competence in cardiac physiology and pathophysiology;
- studying and developing innovative methods of imaging The Advanced Cardiovascular Imaging Fellowship Program is supported by a training grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB).
Cardiovascular Disease Epidemiology Training Program - Wake Forest University School of Medicine
Randi Sullivan, MD, MHS
Wake Forest University School of Medicine
Department of Internal Medicine
Section on Cardiovascular Medicine
Medical Center Boulevard
Winston-Salem, NC 27157
Program Scope and Mission – The purpose of the CVD Epidemiology Training Program, a federally-funded National Research Service Award (NRSA) Institutional Research Training Grant (2 T32 HL076132), is to attract and train a cohort of outstanding physician scientists who will be fluent in the latest developments in cardiovascular disease and able to apply this knowledge to the conduct of new cardiovascular epidemiology and clinical cardiovascular research. Key features of the training program include completion of a Master’s Degree in Clinical and Population Translational Science with a curriculum that also includes formal training in molecular biology and genetics, supplemental training in genomics, proteomics and informatics, joint mentorship with both clinical and basic science faculty, and participation in external NHLBI sponsored short courses in cardiovascular epidemiology, and the genetics of complex heart, lung, and blood disorders.
Clinical Pharmacology Training Program – Vanderbilt University School of Medicine Nashville, TN
Dr. C. Michael Stein, M.B., Ch.B.
Dan May Professor of Medicine and Pharmacology
C. Michael Stein, M.B., Ch.B.
542 Robinson Research Building
Program Scope and Mission – Vanderbilt’s Clinical Pharmacology Fellowship Program is a highly successful program that has produced graduates who are now in prominent positions in academia, industry and regulatory agencies. Our training program is registered with the American Board of Clinical Pharmacology and thus trainees are eligible to sit for the board exam.The training period is at least 2 years, preferably more, and is weighted towards learning through mentored research. In addition, formal coursework and directed learning provide education in core skills. Trainees include individuals with an M.D., Ph.D. or Pharm.D. degree who are planning a career in clinical pharmacology or a career that will be strengthened by significant exposure to clinical pharmacology. A large and diverse faculty in the division, the rich resources at Vanderbilt and our commitment to training has established the outstanding reputation of this Clinical Pharmacology Fellowship Program. Continued excellence of the program depends on our fellows and we invest heavily in their training.
Your program can be listed here - click for more information